Substance abuse, also known as drug use, is a patterned utilization of a medication where the user consumes the substance in amounts or with techniques that are harmful to themselves or other people, and is a kind of substance-related condition. Commonly differing definitions of drug abuse are employed in public areas health, medical and unlawful justice contexts. In some instances unlawful or anti-social behaviour takes place when the individual is under the influence of a drug, and longterm personality alterations in people may occur besides. As well as feasible physical, social, and emotional damage, usage of some medications could also cause criminal penalties, although these vary widely depending on the neighborhood jurisdiction.
Drugs most often connected with this term consist of: liquor, cannabis, barbiturates, benzodiazepines, cocaine, methaqualone, opioids and some substituted amphetamines like methamphetamine and MDMA. The exact reason behind drug abuse is not clear, because of the two prevalent theories being: either a genetic disposition that will be learned from other people, or a habit which if addiction develops, manifests itself as a chronic debilitating illness.
This year about 5% of men and women (230 million) used an illicit substance. Of these 27 million have actually high-risk drug use otherwise called recurrent drug use causing injury to their own health, mental problems, or social problems that place them at risk of those threats. In 2015 substance use problems led to 307,400 fatalities, up from 165,000 deaths in 1990. Of the, the greatest numbers come from alcohol use problems at 137,500, opioid usage problems at 122,100 fatalities, amphetamine usage problems at 12,200 fatalities, and cocaine usage disorders at 11,100.
Public health definitionsa drug user receiving an injection for the opiate heroin
Public medical practioners have attemptedto look at substance usage from a wider viewpoint versus individual, emphasizing the role of culture, tradition, and access. Some health care professionals elect to prevent the terms alcohol or drug «abuse» in favor of language they consider more objective, including «substance and liquor kind problems» or «harmful/problematic use» of drugs. The Health Officers Council of British Columbia — inside their 2005 policy discussion paper, A Public Health method of Drug Control in Canada — has used a public health type of psychoactive substance usage that challenges the simplistic black-and-white construction of binary (or complementary) antonyms «use» vs. «abuse». This model explicitly acknowledges a spectrum useful, ranging from beneficial used to chronic dependence.
Healthcare definitionsA 2010 research ranking various illegal and legal drugs according to statements by drug-harm professionals. Alcohol was found to be the general many dangerous drug.
'Drug abuse' is no much longer a present medical diagnosis in either of the very used diagnostic tools on earth, the United states Psychiatric Association's Diagnostic and Statistical handbook of Mental Disorders (DSM), as well as the World Health Organization's Global Statistical Classification of conditions (ICD).
Value judgmentThis diagram illustrates the correlations among the list of use of 18 appropriate and illegal medications: liquor, amphetamines, amyl nitrite, benzodiazepine, cannabis, chocolate, cocaine, caffeine, break, ecstasy, heroin, ketamine, appropriate highs, LSD, methadone, secret mushrooms (MMushrooms), smoking and volatile substance abuse (VSA). Use is defined as having used the medication at least one time during years 2005–2015. The colored links between medications indicate the correlations with |r|>0.4, in which |r| could be the absolute value for the Pearson correlation coefficient.
Philip Jenkins suggests that there are two problems with the expression «drug abuse». First, just what constitutes a «drug» is debatable. As an example, GHB, a naturally occurring substance in the central nervous system is known as a drug, and is unlawful in lots of nations, while nicotine isn't officially considered a drug generally in most countries.
Second, the word «abuse» suggests an accepted standard of good use for any substance. Consuming an occasional glass of wine is considered acceptable in many Western countries, while consuming a few containers is observed as an abuse. Strict temperance advocates, who may or may not be religiously inspired, would see consuming also one glass as an abuse. Some groups even condemn caffeine used in any quantity. Likewise, adopting the view that any (recreational) use of cannabis or substituted amphetamines comprises drug use implies a choice made that the substance is harmful, in moment amounts. Within the U.S., medications happen lawfully categorized into five groups, schedule We, II, III, IV, or V into the Controlled chemicals Act. The drugs are classified on their deemed prospect of abuse. Using some drugs is strongly correlated. For instance, the intake of seven illicit drugs (amphetamines, cannabis, cocaine, ecstasy, appropriate highs, LSD, and magic mushrooms) is correlated additionally the Pearson correlation coefficient r>0.4 in every couple of them; use of cannabis is highly correlated (r>0.5) with using nicotine (tobacco), heroin is correlated with cocaine (r>0.4), and methadone (r>0.45) is strongly correlated with crack (r>0.5)
Drug misuse is a term utilized commonly when prescription drugs with sedative, anxiolytic, analgesic, or stimulant properties are used for mood alteration or intoxication ignoring the truth that overdose of such medications can sometimes have serious adverse effects. It sometimes involves medication diversion from individual for whom it absolutely was prescribed.
Approved misuse has been defined differently and instead inconsistently centered on status of medication prescription, the uses without a prescription, intentional use to achieve intoxicating impacts, route of management, co-ingestion with alcohol, additionally the presence or lack of dependence signs. Chronic utilization of specific substances causes an alteration into the nervous system referred to as a 'tolerance' to your medication in a way that more of the substance is needed so that you can produce desired results. With some substances, stopping or reducing usage may cause withdrawal signs to occur, but this is extremely influenced by the particular substance under consideration.
The price of prescription medication use is quick overtaking illegal drug used in the usa. In line with the nationwide Institute of drug use, 7 million individuals were taking prescription drugs for nonmedical use in 2010. Among 12th graders, nonmedical prescription drug usage is currently second only to cannabis. Last year, «Nearly 1 in 12 highschool seniors reported nonmedical usage of Vicodin; 1 in 20 reported such utilization of OxyContin.» These two medications have opioids. A 2017 survey of 12th graders in the us, discovered abuse of oxycontin of 2.7 percent, in comparison to 5.5 per cent at its top in 2005. Misuse for the combination hydrocodone/paracetamol is at its cheapest since a peak of 10.5 % in 2003. This decrease might be regarding public health initiatives and decreased accessibility.
Avenues of obtaining prescription medications for misuse are diverse: sharing between relatives and buddies, illegally purchasing medicines at school or work, and often "doctor shopping" to locate multiple doctors to prescribe exactly the same medicine, without familiarity with other prescribers.
Increasingly, law enforcement is holding physicians in charge of prescribing managed substances without fully developing patient controls, such as for example someone «drug contract». Concerned doctors are educating themselves on the best way to determine medication-seeking behavior within their patients, and are also becoming familiar with «red flags» that would alert them to potential prescription drug abuse.
Indications and symptomsRational scale to evaluate the harm of recreational medication useDrugDrug classPhysical
harmHeroinOpioid2.783.002.542.77CocaineCNS stimulant2.332.392.172.30BarbituratesCNS depressant2.232.012.002.08MethadoneOpioid1.862.081.871.94AlcoholCNS depressant1.401.932.211.85KetamineDissociative anesthetic2.001.541.691.74BenzodiazepinesBenzodiazepine1.631.831.651.70AmphetamineCNS stimulant1.811.671.501.66TobaccoTobacco126.96.36.1991.62BuprenorphineOpioid1.601.641.491.58CannabisCannabinoid0.991.511.501.33Solvent drugsInhalant1.281.011.521.274-MTADesigner SSRA1.441.301.061.27LSDPsychedelic188.8.131.521.23MethylphenidateCNS stimulant1.321.250.971.18Anabolic steroidsAnabolic steroid1.450.881.131.15GHBNeurotransmitter0.861.191.301.12EcstasyEmpathogenic stimulant1.051.131.091.09Alkyl nitritesInhalant0.930.870.970.92KhatCNS stimulant0.501.040.850.80Notes towards harm ratingsThe Physical harm, Dependence liability, and Social harm ratings were each computed from the average of three distinct ratings. The highest possible damage score for every single rating scale is 3.0.
Physical damage may be the normal score associated with the scores for severe binge use, chronic use, and intravenous use.
Dependence obligation may be the typical rating for the ratings for strength of pleasure, psychological dependence, and real dependence.
Social damage may be the typical rating associated with the scores for drug intoxication, health-care expenses, as well as other social harms.
Total damage was computed because the average of this Physical harm, Dependence obligation, and Social damage scores.
Depending regarding actual mixture, drug use including alcohol can result in health issues, social issues, morbidity, injuries, unprotected sex, physical violence, fatalities, motor vehicle accidents, homicides, suicides, real dependence or emotional addiction.
There is a high rate of suicide in alcoholics along with other drug abusers. The reason why believed to result in the increased risk of suicide include the long-term punishment of alcohol along with other medications causing physiological distortion of mind chemistry plus the social isolation. Another factor could be the acute intoxicating aftereffects of the drugs could make suicide almost certainly going to happen. Suicide can also be quite typical in adolescent liquor abusers, with 1 in 4 suicides in adolescents being linked to alcohol punishment. In the US, approximately 30per cent of suicides are linked to alcohol abuse. Alcohol abuse normally connected with increased dangers of committing unlawful offences including son or daughter punishment, domestic physical violence, rapes, burglaries and assaults.
Substance abuse, including alcohol and prescription drugs, can cause symptomatology which resembles psychological infection. This can occur both in the intoxicated state and in addition during the withdrawal state. In some cases these substance induced psychiatric disorders can continue long after detoxification, such as for instance extended psychosis or despair after amphetamine or cocaine abuse. A protracted withdrawal syndrome can also happen with signs persisting for months after cessation useful. Benzodiazepines would be the most notable medication for inducing prolonged withdrawal effects with symptoms often persisting for a long time after cessation of use. Both liquor, barbiturate plus benzodiazepine withdrawal could possibly be deadly. Punishment of hallucinogens can trigger delusional alongside psychotic phenomena very long after cessation of use.
Cannabis may trigger panic disorder during intoxication sufficient reason for continued usage, it would likely cause a situation similar to dysthymia. Researchers are finding that daily cannabis use additionally the use of high-potency cannabis are individually related to a higher possibility of developing schizophrenia as well as other psychotic disorders.
Serious anxiety and despair can be induced by sustained alcohol punishment, that most cases abates with prolonged abstinence. Even sustained moderate liquor usage may increase anxiety and despair amounts in certain individuals. Generally these medication induced psychiatric disorders fade with prolonged abstinence.
Impulsivity is characterized by actions based on unexpected desires, whims, or inclinations instead of careful idea. Those with substance abuse have greater levels of impulsivity, and people who utilize multiple drugs tend to be more impulsive. A number of studies utilising the Iowa gambling task as a measure for impulsive behavior found that medication making use of populations made more high-risk alternatives compared to healthy settings. There's a hypothesis your loss of impulse control may be due to impaired inhibitory control resulting from drug induced modifications that happen in the front cortex. The neurodevelopmental and hormonal alterations that happen during adolescence may modulate impulse control that could perhaps induce the experimentation with drugs and may also result in the street of addiction. Impulsivity is considered to be a facet trait inside neuroticism character domain (overindulgence/negative urgency) that will be prospectively associated with the growth of drug abuse.
Screening and assessment
There are many different testing tools that have been validated to be used with adolescents such as the CRAFFT Screening ensure that you in grownups the CAGE questionnaire.
Some recommendations for assessment tools for substance abuse in pregnancy consist of which they simply take under ten full minutes, must certanly be used routinely, consist of an educational component. Tools appropriate women that are pregnant consist of i.a. 4Ps, T-ACE, TWEAK, TQDH (Ten-Question consuming History), and AUDIT.
from applied behavior analysis literary works, behavioral psychology, and from randomized clinical trials, several evidenced based interventions have emerged: behavioral marital therapy, motivational Interviewing, community reinforcement approach, publicity therapy, contingency management They help suppress cravings and mental anxiety, enhance consider treatment and brand new learning behavioral abilities, simplicity withdrawal symptoms and minimize the likelihood of relapse.
In children and adolescents, intellectual behavioral treatment (CBT) and family members therapy presently gets the many research evidence the treatment of drug abuse problems. Well-established studies likewise incorporate environmental family-based therapy and team CBT. These remedies is administered in many different different platforms, all of which has varying degrees of research support analysis shows that what makes group CBT most effective is that it encourages the development of social abilities, developmentally appropriate emotional regulatory skills alongside social abilities. A couple of integrated therapy models, which combines parts from various types of therapy, have also been viewed as both well-established or probably effective. A study on maternal alcohol and drug use indicates that built-in treatment programs have produced significant results, causing greater negative results on toxicology screens. Furthermore, brief school-based interventions happen discovered to work in reducing adolescent liquor and cannabis use and abuse.Motivational interviewing can also be effective in treating substance usage disorder in adolescents.
Alcoholics Anonymous and Narcotics Anonymous are perhaps one of the most well regarded self-help organizations in which members support both not to ever use alcohol.Social abilities are somewhat weakened in individuals experiencing alcoholism as a result of the neurotoxic effects of alcohol on the brain, especially the prefrontal cortex part of the brain. It is often recommended that social abilities training adjunctive to inpatient treatment of liquor dependence might be efficacious, including managing the social environment.
some medicines were approved for the remedy for substance abuse. These include replacement treatments such as for example buprenorphine and methadone also antagonist medications like disulfiram and naltrexone in either quick acting, or the more recent long acting kind. Some other medications, often ones initially used in other contexts, have also been shown to be effective including bupropion and modafinil. Methadone and buprenorphine are occasionally always treat opiate addiction. These medications are utilized as substitutes for other opioids and still cause withdrawal signs.
Antipsychotic medicines haven't been found become useful. Acamprostate is a glutamatergic NMDA antagonist, which supports liquor withdrawal symptoms because alcohol withdrawal is connected with a hyperglutamatergic system.
Dual diagnosisMain article: Dual diagnosis
It is common for people with drugs use disorder to possess other emotional problems. The terms “dual diagnosis” or “co-occurring problems,” relate to having a mental health insurance and substance usage disorder on top of that. According to the British Association for Psychopharmacology (BAP), “symptoms of psychiatric problems such as for instance depression, anxiety and psychosis will be the guideline as opposed to the exception in patients misusing drugs and/or liquor.”
Individuals who have actually a comorbid emotional disorder frequently have a poor prognosis if either disorder is untreated. Historically many people with twin diagnosis either received therapy only for one of their disorders or they didn’t receive any treatment all. However, considering that the 1980s, there has been a push towards integrating mental health and addiction therapy. In this technique, neither condition is considered main and both are treated simultaneously by the same provider.
EpidemiologyDisability-adjusted life year for medication use disorders per 100,000 inhabitants in 2004. no information <40 40–80 80–120 120–160 160–200 200–240 240–280 280–320 320–360 360–400 400–440 >440complete recorded alcohol per capita consumption (15+), in litres of pure alcohol
The initiation of drug and alcohol use is probably to happen during adolescence, plus some experimentation with substances by older adolescents is typical. As an example, results from 2010 Monitoring the long run study, a nationwide research on rates of substance use within the United States, show that 48.2per cent of 12th graders report having used an illicit medication at some time within their life. Inside thirty days ahead of the survey, 41.2% of 12th graders had consumed liquor and 19.2percent of 12th graders had smoked tobacco cigarettes. During 2009 in the usa about 21percent of kids have taken prescription drugs without a prescription. And earlier in the day in 2002, the entire world wellness Organization estimated that around 140 million everyone was alcohol reliant and another 400 million with alcohol-related problems.
Studies have shown your large most adolescents will phase away from medication usage before it becomes problematic. Hence, although rates of general usage are high, the portion of adolescents whom meet requirements for drug abuse is dramatically reduced (near to 5per cent). According to BBC, «internationally, the UN quotes there are more than 50 million regular users of morphine diacetate (heroin), cocaine and synthetic drugs.»
Over 70,200 People in america died from medication overdoses in 2017. Among these, the sharpest increase took place among deaths associated with fentanyl and synthetic opioids (28,466 fatalities). See charts below.
Total yearly U.S. medication deaths.
US yearly overdose fatalities, plus the medications included.
APA, AMA, and NCDA
In 1932, the American Psychiatric Association created a meaning which used legality, social acceptability, and cultural familiarity as qualifying factors:
…as a general rule, we reserve the expression drug use to apply carefully to the illegal, nonmedical usage of a restricted amount of substances, many of them medications, that have properties of altering the mental state in many ways which can be considered by social norms and defined by statute become inappropriate, unwelcome, harmful, threatening, or, at minimum, culture-alien.
In 1966, the American Medical Association's Committee on Alcoholism and Addiction defined punishment of stimulants (amphetamines, mainly) with regards to 'medical supervision':
…'use' refers to the proper place of stimulants in medical training; 'misuse' applies to the medic's part in starting a potentially dangerous span of treatment; and 'abuse' means self-administration of these drugs without medical guidance and especially in big doses which could result in emotional dependency, threshold and irregular behavior.
In 1973, the National Commission on Marijuana and Drug Abuse stated:
...drug abuse may reference any sort of medication or chemical without respect to its pharmacologic actions. Its an eclectic concept having only one uniform connotation: societal disapproval.… The Commission believes that the term drug use should be deleted from formal pronouncements and public policy discussion. The word does not have any practical utility and has now become no more than an arbitrary codeword for that drug use that is currently considered wrong.
the initial version associated with the American Psychiatric Association's Diagnostic and Statistical handbook of Mental Disorders (posted in 1952) grouped liquor and drug abuse under Sociopathic Personality Disturbances, that have been thought to be symptoms of deeper emotional disorders or ethical weakness. The next edition, posted in 1980, was the first to ever recognize drug abuse (including substance abuse) and substance dependence as conditions split up from substance abuse alone, bringing in social and social factors. The meaning of dependence emphasised threshold to medications, and withdrawal from their website as key components to diagnosis, whereas punishment ended up being thought as «problematic use with social or work-related impairment» but without withdrawal or tolerance.
In 1987, the DSM-IIIR category «psychoactive drug abuse,» including former ideas of drug use means «a maladaptive pattern of use indicated by...continued usage despite familiarity with having a persistent or recurrent social, occupational, mental or real issue which triggered or exacerbated by the utilization (or by) recurrent use in circumstances where its actually hazardous.» It's a residual category, with dependence taking precedence whenever applicable. It absolutely was the initial definition to provide equal weight to behavioural and physiological factors in diagnosis. By 1988, the DSM-IV defines substance dependence as «a syndrome involving compulsive use, with or without threshold and withdrawal»; whereas drug abuse is «problematic usage without compulsive usage, significant tolerance, or withdrawal.» Drug abuse are damaging to your health and may even be deadly in certain scenarios. By 1994, The fourth version of Diagnostic and Statistical Manual of Mental Disorders (DSM) released by the American Psychiatric Association, the DSM-IV-TR, describes substance dependence as «when a person continues used of alcohol or other drugs despite issues linked to utilization of the substance, substance dependence might be diagnosed.» followed closely by criteria for the diagnose
DSM-IV-TR defines drug abuse as:
- A. A maladaptive pattern of substance use ultimately causing clinically significant disability or stress, as manifested by one (or higher) of this after, occurring within a 12-month duration:
- Recurrent substance use resulting in a deep failing to satisfy major role obligations at the job, school, or house (e.g., duplicated absences or poor work performance regarding substance usage; substance-related absences, suspensions or expulsions from school; neglect of children or household)
- Recurrent substance use within circumstances where it's physically dangerous (e.g., driving an automobile or running a device when reduced by substance use)
- Recurrent substance-related appropriate problems (e.g., arrests for substance-related disorderly conduct)
- Continued substance usage despite having persistent or recurrent social or interpersonal issues triggered or exacerbated by the results of substance (age.g., arguments with spouse about consequences of intoxication, physical fights)
- B. The outward symptoms haven't met the requirements for Substance Dependence for this class of substance.
The fifth version associated with DSM (DSM-5), premiered in 2013, and it revisited this terminology. The key modification ended up being a transition from abuse/dependence terminology. In the DSM-IV age, punishment had been seen as an early kind or less dangerous as a type of the illness characterized using the dependence requirements. However, the APA's 'dependence' term, as noted above, does not always mean that physiologic dependence exists but alternatively implies that an illness state is present, one which most would reference as an addicted state. Numerous involved observe that the terminology has usually led to confusion, both within the medical community and with the average man or woman. The United states Psychiatric Association requested input concerning how the terminology of the illness should really be modified since it moves ahead with DSM-5 conversation. Into the DSM-5, drug abuse and substance dependence were merged into the category of substance use disorders plus they now much longer occur as specific concepts. While drug abuse and dependence had been either present or not, substance use disorder has three degrees of severity: moderate, moderate and severe.
Community and culture
Legal approachesRelated articles: medication control law, Prohibition (drugs), Arguments pros and cons medication prohibition, Harm reduction
Most governments have actually created legislation to criminalize certain forms of medication usage. These medications are often called «illegal drugs» but generally what exactly is unlawful is their unlicensed manufacturing, circulation, and possession. These drugs are also called «controlled substances». Even for easy possession, legal punishment can be very serious (such as the death penalty in some nations). Laws vary across nations, and even within them, and possess fluctuated commonly throughout history.
Efforts by government-sponsored drug control policy to interdict medication supply and eradicate drug use have already been largely unsuccessful.In spite of the huge efforts by the U.S., medication supply and purity has now reached an all-time high, using the vast majority of resources used on interdiction and law enforcement in the place of general public health. In the United States, the amount of nonviolent drug offenders in jail exceeds by 100,000 the full total incarcerated populace inside EU, even though the EU has 100 million more residents.
Despite medication legislation (or maybe because of it), big, organized unlawful drug cartels run worldwide. Advocates of decriminalization argue that drug prohibition makes drug working a lucrative company, leading to much of the associated criminal task.
Policymakers attempt to realize the general expenses of drug-related interventions. An appropriate drug policy hinges on the evaluation of drug-related general public spending centered on a classification system where costs are properly identified.
Labelled drug-related expenses are defined as the direct in the pipeline investing that reflects the voluntary engagement associated with the state in the area of illicit medications. Direct general public expenditures clearly labeled as drug-related can be easily traced back by exhaustively reviewing official accountancy papers like nationwide spending plans and year-end reports. Unlabelled expenditure refers to unplanned spending and is believed through modeling techniques, according to a top-down budgetary procedure. Beginning with overall aggregated expenditures, this procedure estimates the percentage causally due to substance abuse (Unlabelled Drug-related spending = Overall Expenditure × Attributable Proportion). For example, to calculate the jail drug-related expenditures in certain nation, two elements will be necessary: the entire prison expenditures in the united states for certain duration, and attributable proportion of inmates considering drug-related issues. The product associated with two gives a rough estimate which can be compared across different countries.
As area of the reporting exercise corresponding to 2005, the European Monitoring Centre for Drugs and Drug Addiction's system of national points of interest set up inside 27 European Union (EU) Member States, Norway, additionally the applicants countries towards the EU, had been required to recognize labeled drug-related public spending, within nation degree.
This was reported by 10 nations classified in line with the functions of federal government, amounting to an overall total of EUR 2.17 billion. In general, the highest proportion of the total arrived in the federal government functions of Health (66per cent) (age.g. medical solutions), and Public purchase and Safety (POS) (20%) (e.g. authorities solutions, legislation courts, prisons). By country, the average share of GDP ended up being 0.023per cent for wellness, and 0.013per cent for POS. However, these shares varied considerably across countries, including 0.00033% in Slovakia, up to 0.053percent of GDP in Ireland when it comes to wellness, and from 0.003percent in Portugal, to 0.02per cent in the UK, regarding POS; nearly a 161-fold difference between the greatest while the lowest nations for wellness, and a 6-fold huge difference for POS. How come Ireland while the British spend so much in health insurance and POS, or Slovakia and Portugal therefore little, in GDP terms?
To react to this concern also to make an extensive assessment of drug-related public expenditure across countries, this study compared Health and POS investing and GDP in the 10 reporting nations. Results discovered suggest GDP become a major determinant associated with the Health and POS drug-related general public expenses of a country. Labelled drug-related general public spending showed an optimistic association because of the GDP over the nations considered: r = 0.81 in the case of Health, and r = 0.91 for POS. The portion change in health insurance and POS expenditures considering a one per cent increase in GDP (the earnings elasticity of need) was calculated become 1.78% and 1.23percent correspondingly.
Being extremely income elastic, Health and POS expenses can be viewed luxury goods; as a nation becomes wealthier it freely spends proportionately more on drug-related health and public purchase and safety interventions.
great britain Home Office estimated your social and financial price of drug abuse towards UK economy with regards to criminal activity, absenteeism and vomiting is more than £20 billion a year.However, great britain office at home will not estimate exactly what portion of those crimes are unintended consequences of medication prohibition (crimes to maintain expensive medication consumption, high-risk production and dangerous circulation), nor what's the price of enforcement. Those aspects are essential for the full analysis associated with the economics of prohibition.
(billions of dollars)19921071993111199411719951251996130199713419981401999151200016120011702002181
These figures represent general financial costs, and this can be divided in three major elements: health costs, efficiency losses and non-health direct expenses.
- Health-related costs were projected to complete $16 billion in 2002.
- Productivity losings were approximated at $128.6 billion. In comparison to another costs of drug abuse (which include direct expenditures for items and solutions), this value reflects a loss of possible resources: work with the labor market plus in household production which was never ever done, but could fairly be expected to own been done absent the effect of drug use.
- The non-health direct expenditures primarily concern expenses linked to the unlawful justice system and criminal activity victim costs, and include a modest degree of expenses for administration of social welfare system. The sum total for 2002 was calculated at $36.4 billion. The biggest detail by detail component of these expenses is for state and federal corrections at $14.2 billion, which can be mainly for the operation of prisons. Another $9.8 billion ended up being used on state and local authorities security, followed closely by $6.2 billion for federal supply reduction initiatives.
According to a report through the Agency for Healthcare Research and Quality (AHRQ), Medicaid had been billed for a significantly higher amount of hospitals stays for Opioid drug overuse than Medicare or personal insurance in 1993. By 2012, the differences were diminished. Over the same time, Medicare had the absolute most quick growth in quantity of medical center stays.
Immigrants and refugees
Immigrant and refugees have usually been under great anxiety, physical injury and despair and anxiety because of separation from family members usually characterize the pre-migration and transportation phases, followed closely by «cultural dissonance,» language obstacles, racism, discrimination, financial adversity, overcrowding, social isolation, and loss of status and difficulty obtaining work and worries of deportation are common. Refugees often encounter issues concerning the health and safety of family members left out and doubt about the chance of returning to their country of origin. For a few, drug abuse functions as a coping apparatus to try to handle these stressors.
Immigrants and refugees may bring the substance usage and punishment habits and actions of these nation of beginning, or adopt the attitudes, habits, and norms regarding substance use and abuse which exist in the dominant tradition into that they are entering.
Street kiddies in a lot of developing countries are a higher risk team for substance abuse, particularly solvent punishment. Drawing on research in Kenya, Cottrell-Boyce argues that «drug utilize amongst street kiddies is primarily functional – dulling the senses contrary to the hardships of life in the road – but can also provide a hyperlink on support framework of the ‘street family’ peer group as a potent icon of provided experience.»
so that you can keep high-quality performance, some performers simply take substances. Some performers just take medications or alcohol to cope with the stress of performing. As a group they will have a higher rate of substance abuse. The most common compound that is mistreated by pop artists is cocaine, because of its neurological results. Stimulants like cocaine enhance alertness and cause feelings of euphoria, and will for that reason make the performer feel as if they in some ways ‘own the stage’. A good way by which drug abuse is harmful for a performer (musicians especially) is if the substance being mistreated is aspirated. The lung area are an essential organ employed by vocalists, and addiction to cigarettes may seriously harm the quality of their performance. Smoking causes harm to alveoli, which are in charge of absorbing air.
Substance abuse can be another contributing factor that impacts real and mental health of veterans. Substance abuse could also damage individual relationships families and induce financial trouble. There is evidence to suggest that substance abuse disproportionately affects the homeless veteran population. A 2015 Florida research compared factors behind homelessness between veterans and non veteran populations in a self reporting questionnaire. The results through the research found that 17.8percent of this homeless veteran participants attributed their homelessness to alcohol and medication associated issues in comparison to simply 3.7per cent associated with the non-veteran homeless group.
A 2003 research unearthed that homelessness was associated with use of help from family/friends and services. However, this relationship was not real when you compare homeless individuals who'd an ongoing substance-use problems. The U.S. Department of Veterans Affairs provide a summary of treatments for veterans with substance usage condition. For remedies that do not involve medicine, they provide a therapeutic options that focused on finding outside organizations and “looking at how substance use issues may relate with other problems particularly PTSD and depression”.
- Addictive personality
- Alcohol abuse
- Combined drug intoxication
- Controlled Substances Act
- Drug addiction
- Drug overdose
- List of controlled drugs within the United Kingdom
- List of deaths from drug overdose and intoxication
- damage reduction
- Low-threshold treatment programs
- Needle-exchange programme
- Poly drug use
- Polysubstance abuse
- Substance use disorder
- ^ a b c d e f g Nutt, D.; King, L. A.; Saulsbury, W.; Blakemore, C. (2007). «Development of a rational scale to evaluate the damage of drugs of possible misuse». The Lancet. 369 (9566): 1047–1053. doi:10.1016/S0140-6736(07)60464-4. PMID 17382831.
- ^ a b c «World Drug Report 2012» (PDF). UN. Retrieved 27 September 2016.
- ^ a b «EMCDDA | informative data on the high-risk medication use (HRDU) (formerly 'problem medication use' (PDU)) key indicator». www.emcdda.europa.eu. Retrieved 2016-09-27.
- ^ a b c GBD 2015 Mortality and Causes of Death, Collaborators. (8 October 2016). «Global, regional, and nationwide endurance, all-cause mortality, and cause-specific mortality for 249 factors behind death, 1980–2015: a systematic analysis for the international Burden of infection learn 2015». Lancet. 388 (10053): 1459–1544. doi:10.1016/S0140-6736(16)31012-1. PMC 5388903. PMID 27733281.
- ^ Ksir, Oakley Ray; Charles (2002). Medications, society, and individual behavior (9th ed.). Boston [u.a.]: McGraw-Hill. ISBN 978-0072319637.
- ^ (2002). Mosby's Healthcare, Nursing & Allied Wellness Dictionary. Sixth Edition. Drug abuse meaning, p. 552. Nursing diagnoses, p. 2109.ISBN 0-323-01430-5.
- ^ «Addiction is a Chronic Disease». Archived through the original on 24 June 2014. Retrieved 2 July 2014.
- ^ GBD 2013 Mortality and results in of Death, Collaborators (17 December 2014). «Global, local, and nationwide age-sex particular all-cause and cause-specific mortality for 240 factors behind death, 1990–2013: a systematic analysis for the international Burden of Disease research 2013». Lancet. 385 (9963): 117–71. doi:10.1016/S0140-6736(14)61682-2. PMC 4340604. PMID 25530442.
- ^ «A Public Wellness Approach» (PDF). Retrieved 1 April 2017.
- ^ Nutt, David J; King, Leslie A; Phillips, Lawrence D (November 2010). «Drug harms into the UK: a multicriteria choice analysis». The Lancet. 376 (9752): 1558–1565. CiteSeerX 10.1.1.690.1283. doi:10.1016/S0140-6736(10)61462-6. PMID 21036393.
- ^ a b c E. Fehrman, A. K. Muhammad, E. M. Mirkes, V. Egan, A. N. Gorban,The Five Factor type of character and evaluation of medication usage danger, arXiv:1506.06297 [stat.AP], 2015
- ^ Philip Jenkins, Synthetic panics: the symbolic politics of designer medications, NYU Press, 1999,ISBN 0-8147-4244-0, pp. ix–x
- ^ Barrett SP, Meisner JR, Stewart SH (November 2008). «exactly what comprises prescription medication abuse? Dilemmas and pitfalls of present conceptualizations» (PDF). Curr substance abuse Rev. 1 (3): 255–62. doi:10.2174/1874473710801030255. PMID 19630724. Archived through the original (PDF) on 2010-06-15.
- ^ McCabe SE, Boyd CJ, Teter CJ (June 2009). «Subtypes of nonmedical prescription medication misuse». Drug Alcohol Depend. 102 (1–3): 63–70. doi:10.1016/j.drugalcdep.2009.01.007. PMC 2975029. PMID 19278795.
- ^ Antai-Otong, D. 2008. Psychiatric Nursing: Biological and Behavioral Concepts. 2nd edition. Canada: Thompson Delmar Learning
- ^ «The Approved Drug Abuse Epidemic». PDMP Center of Excellence. 2010–2013.
- ^ «Topics in quick: approved Drug Abuse» NIDA, December 2011.
- ^ a b c «Vaping popular among teenagers; opioid misuse at historic lows». National Institute on Substance Abuse. 14 December 2017. Retrieved 10 April 2019.
- ^ «Combating Prescription drug use in Your Practice» Archived 2012-06-18 at Wayback Machine Aubrey Westgate, Physicians Practice, June 2012.
- ^ Burke PJ, O'Sullivan J, Vaughan BL (November 2005). «Adolescent substance usage: brief interventions by crisis care providers». Pediatr Emerg Care. 21 (11): 770–6. doi:10.1097/01.pec.0000186435.66838.b3. PMID 16280955.
- ^ O'Connor, Rory; Sheehy, Noel (29 January 2000). Understanding suicidal behavior. Leicester: BPS Books. pp. 33–36. ISBN 978-1-85433-290-5.
- ^ Isralowitz, Richard (2004). Medication use: a reference handbook. Santa Barbara, Calif.: ABC-CLIO. pp. 122–123. ISBN 978-1-57607-708-5.
- ^ University of Miami: Substance Abuse, Substance Abuse and health threats
- ^ Di Forti M, Marconi the, Carra E, Fraietta S, Trotta the, Bonomo M, Bianconi F, Gardner-Sood P, O'Connor J, Russo M, Stilo SA, Marques TR, Mondelli V, Dazzan P, Pariante C, David like, Gaughran F, Atakan Z, Iyegbe C, Powell J, Morgan C, Lynskey M, Murray RM (2015). «Proportion of clients in south London with first-episode psychosis owing to use of high potency cannabis: a case-control study» (PDF). Lancet Psychiatry. 2 (3): 233–8. doi:10.1016/S2215-0366(14)00117-5. PMID 26359901.
- ^ Marta Di Forti (17 December 2013). «Daily Use, Especially of High-Potency Cannabis, Drives the sooner Onset of Psychosis in Cannabis Users». Schizophrenia Bulletin. 40 (6): 1509–1517. doi:10.1093/schbul/sbt181. PMC 4193693. PMID 24345517.
- ^ Evans, Katie; Sullivan, Michael J. (1 March 2001). Double Diagnosis: Counseling the Mentally Ill Substance Abuser (second ed.). Guilford Press. pp. 75–76. ISBN 978-1-57230-446-8.
- ^ «Impulsivity». The complimentary Dictionary.
- ^ a b Gerard Moeller M.D., Barratt Ernest S., Ph, Dougherty Donald M., Ph, Schmitz Joy M., Ph, Swann Alan C. (2001). «Psychiatric Facets Of Impulsivity». The United States Journal of Psychiatry. 158 (11): 1783–93. doi:10.1176/appi.ajp.158.11.1783. PMID 11691682. Archived from original on April 15, 2013.CS1 maint: Multiple names: authors list (link)
- ^ Bishara AJ, Pleskac TJ, Fridberg DJ, Yechiam E, Lucas J, Busemeyer JR, Finn PR, Stout JC (2009). «Similar Processes Despite Divergent Behavior in Two popular Measures of Risky choice Making». J Behav Decis Mak. 22 (4): 435–454. doi:10.1002/bdm.641. PMC 3152830. PMID 21836771.
- ^ Genetic impacts on impulsivity, danger taking, anxiety responsivity and vulnerability to drug use and addiction
- ^ Chambers RA, Taylor JR, Potenza MN (2003). «Developmental neurocircuitry of motivation in adolescence: a crucial period of addiction vulnerability». Am J Psychiatry. 160 (6): 1041–52. doi:10.1176/appi.ajp.160.6.1041. PMC 2919168. PMID 12777258.
- ^ Jeronimus B.F.; Kotov, R.; Riese, H.; Ormel, J. (2016). «Neuroticism's prospective association with psychological disorders halves after adjustment for baseline symptoms and psychiatric history, but the adjusted association hardly decays with time: a meta-analysis on 59 longitudinal/prospective studies with 443 313 participants». Psychological Medicine. 46 (14): 2883–2906. doi:10.1017/S0033291716001653. PMID 27523506.
- ^ Morse, Barbara (1997). Screening for Substance Abuse During Pregnancy: Improving Care, Improving Health (PDF). pp. 4–5. ISBN 978-1-57285-042-2.
- ^ O'Donohue, W; K.E. Ferguson (2006). «Evidence-Based Practice in Psychology and Behavior Analysis». The Behavior Analyst Today. 7 (3): 335–350. doi:10.1037/h0100155. Retrieved 2008-03-24.
- ^ Chambless, D.L.; et al. (1998). «An improvement on empirically validated therapies» (PDF). Clinical Psychology. 49: 5–14. Retrieved 2008-03-24.
- ^ «NIH Senior Health „Build With You in Mind“: Survey». nihseniorhealth.gov. Archived from initial on 2015-08-11. Retrieved 29 July 2015.
- ^ «Association for Behavioral and Cognitive Therapies – What is CBT?». Archived through the original on 2010-04-21.
- ^ «Association for Behavioral and Cognitive Therapies – what's Family Therapy?». Archived from original on 2010-06-13.
- ^ a b Hogue, A; Henderson, CE; Ozechowski, TJ; Robbins, MS (2014). «Evidence base on outpatient behavioral remedies for adolescent substance use: updates and suggestions 2007–2013». Journal of Clinical Child and Adolescent Psychology. 43 (5): 695–720. doi:10.1080/15374416.2014.915550. PMID 24926870.
- ^ «Association for Behavioral and Cognitive Therapies – treatment plan for Substance utilize Disorders». Archived from the initial on 2010-04-21.
- ^ Engle, Bretton; Macgowan, Mark J. (2009-08-05). «A Critical Review of Adolescent Drug Abuse Group Treatments». Journal of Evidence-Based Social Work. 6 (3): 217–243. doi:10.1080/15433710802686971. ISSN 1543-3714. PMID 20183675.
- ^ a b «Maternal substance usage and built-in treatment programs for women with substance abuse issues and their children: a meta-analysis». www.crd.york.ac.uk. Retrieved 2016-03-09.
- ^ Carney, Tara; Myers, Bronwyn J; Louw, Johann; Okwundu, Charles I (2016-01-20). «Brief school-based interventions and behavioural results for substance-using adolescents». Cochrane Database of Systematic Reviews (1): CD008969. doi:10.1002/14651858.cd008969.pub3. PMID 26787125.
- ^ Jensen, Chad D.; Cushing, Christopher C.; Aylward, Brandon S.; Craig, James T.; Sorell, Danielle M.; Steele, Ric G. (2011). «Effectiveness of motivational interviewing interventions for adolescent substance use behavior change: A meta-analytic review». Journal of Consulting and Clinical Psychology. 79 (4): 433–440. doi:10.1037/a0023992. PMID 21728400.
- ^ Barnett, Elizabeth; Sussman, Steve; Smith, Caitlin; Rohrbach, Louise A.; Spruijt-Metz, Donna (2012). «Motivational Interviewing for adolescent substance usage: A review of the literature». Addictive Behaviors. 37 (12): 1325–1334. doi:10.1016/j.addbeh.2012.07.001. PMC 3496394. PMID 22958865.
- ^ «Self-Help Groups Article». Retrieved May 27, 2015.
- ^ Uekermann J, Daum I (May 2008). «Social cognition in alcoholism: a link to prefrontal cortex disorder?». Addiction. 103 (5): 726–35. doi:10.1111/j.1360-0443.2008.02157.x. PMID 18412750.
- ^ Purvis G.; MacInnis D. M. (2009). «Implementation associated with Community Reinforcement Approach (CRA) in a Long-Standing Addictions Outpatient Clinic» (PDF). Journal of Behavior research of Sports, Health, Fitness and Behavioral Medicine. 2: 133–44. Archived from the initial (PDF) on 2010-12-29.
- ^ «Current Pharmacological Treatment Designed For Alchhol Abuse». The Ca Evidence-Based Clearinghouse. 2006–2013.
- ^ James W. Kalat Biological therapy 11th edition pg.78
- ^ Maglione, M; Maher, AR; Hu, J; Wang, Z; Shanman, R; Shekelle, PG; Roth, B; Hilton, L; Suttorp, MJ; Ewing, BA; Motala, A; Perry, T (September 2011). «Off-Label Use of Atypical Antipsychotics: An Update [Internet]». Agency for Healthcare analysis and Quality (US). PMID 22132426. Report No.: 11-EHC087-EF.
- ^ Lingford-Hughes AR, Welch S, Peters L, Nutt DJ, British Association for Psychopharmacology, Expert Reviewers Group (2012-07-01). «BAP updated recommendations: evidence-based guidelines the pharmacological management of substance abuse, harmful usage, addiction and comorbidity: recommendations from BAP». Journal of Psychopharmacology. 26 (7): 899–952. doi:10.1177/0269881112444324. ISSN 0269-8811. PMID 22628390.
- ^ a b Lingford-Hughes A. R.; Welch S.; Peters L.; Nutt D. J. (2012). «BAP updated recommendations: evidence-based directions for the pharmacological handling of drug abuse, harmful usage, addiction and comorbidity: recommendations from BAP» (PDF). Journal of Psychopharmacology. 26 (7): 899–952. doi:10.1177/0269881112444324. PMID 22628390. Archived from initial (PDF) on 2012-12-03.
- ^ a b Peterson Ashley L (2013). «Integrating Mental Health and Addictions Services to enhance customer Outcomes». Issues in Mental Health Nursing. 34 (10): 752–756. doi:10.3109/01612840.2013.809830. PMID 24066651.
- ^ Worldwide Status Report on Alcohol 2004
- ^ a b Johnston, L. D., O’Malley, P. M., Bachman, J. G., & Schulenberg, J. E. (2011). Monitoring the long run national outcomes on adolescent drug use: summary of key findings, 2010. Ann Arbor: Institute for Personal Analysis, The University of Michigan.
- ^ «CDC Newsroom pr release June 3, 2010».
- ^ Barker, P. ed. 2003. Psychiatric and mental health nursing: the art and caring. London: Arnold. pp297
- ^ Effective Child Therapy: Drug Abuse and Dependence. Copyright 2012 Archived 2013-05-03 on Wayback Machine
- ^ "Drug Trade". BBC News.
- ^ a b c d Overdose Death Rates. By Nationwide Institute on Drug Use (NIDA).
- ^ Glasscote, R.M., Sussex, J.N., Jaffe, J.H., Ball, J., Brill, L. (1932). Treating substance abuse for individuals like you...: tools, issues, leads. Washington, D.C.: Joint Information provider for the American Psychiatric Association together with National Association for psychological state.
- ^ Second Report regarding the National Commission on Marihuana and substance abuse; medication used in America: Problem In Perspective (March 1973), p.13
- ^ Transformations: Substance Drug Abuse
- ^ DSM-IV & DSM-IV-TR:Substance Dependence Archived 2011-09-27 within Wayback Machine
- ^ American Psychiatric Association (1994). Diagnostic and statistical manual of psychological disorders (4th edition). Washington, DC.
- ^ Hasin, Deborah S.; O’Brien, Charles P.; Auriacombe, Marc; Borges, Guilherme; Bucholz, Kathleen; Budney, Alan; Compton, Wilson M.; Crowley, Thomas; Ling, Walter (2013-08-01). «DSM-5 Criteria for Substance utilize Disorders: guidelines and Rationale». United states Journal of Psychiatry. 170 (8): 834–851. doi:10.1176/appi.ajp.2013.12060782. ISSN 0002-953X. PMC 3767415. PMID 23903334.
- ^ «Diagnostic and analytical handbook of Mental Disorders: DSM-5 (5th edition)2014 102 Washington, DC American Psychiatric Association 2013 xliv+947 pp. 9780890425541(hbck);9780890425558(pbck) £175 $199 (hbck); £45 $69 (pbck)». Guide Reviews. 28 (3): 36–37. 11 March 2014. doi:10.1108/rr-10-2013-0256.
- ^ Copeman M (April 2003). «Drug supply and drug abuse». CMAJ. 168 (9): 1113, writer answer 1113. PMC 153673. PMID 12719309. Archived from initial on 2009-09-06.
- ^ Wood E, Tyndall MW, Spittal PM, et al. (January 2003). «Impact of supply-side policies for control of illicit medications in the face of the AIDS and overdose epidemics: research of a massive heroin seizure». CMAJ. 168 (2): 165–9. PMC 140425. PMID 12538544.
- ^ Bewley-Taylor, Dave, Hallam, Chris, Allen Rob. The Beckley Foundation Drug Policy Programme: The Incarceration of Drug Offenders: A Synopsis. March 2009.
- ^ a b c Prieto L (2010). «Labelled drug-related public spending with regards to gross domestic item (gdp) in European countries: an extra good?». Drug abuse Treatment, Prevention, and Policy. 5: 9. doi:10.1186/1747-597x-5-9. PMC 2881082. PMID 20478069.
- ^ «NHS and Drug Abuse». Nationwide Health Service (NHS). March 22, 2010. Retrieved March 22, 2010.
- ^ «Home workplace | Tackling Drugs Changing Lives | Drugs in the workplace». 2007-06-09. Archived through the original on 2007-06-09. Retrieved 2016-09-19.
- ^ Thornton, Mark. «The Economics of Prohibition».
- ^ The economic expenses of drug use within the United States
- ^ Owens PL, Barrett ML, Weiss AJ, Washington RE, Kronick R (August 2014). «Hospital Inpatient Utilization linked to Opioid Overuse Among grownups, 1993–2012». HCUP Statistical Quick #177. Rockville, MD: Agency for Healthcare Research and Quality.
- ^ Drachman, D. (1992). «A stage-of-migration framework for solution to immigrant populations». Social Work. 37 (1): 68–72. doi:10.1093/sw/37.1.68.
- ^ Pumariega A. J.; Rothe E.; Pumariega J. B. (2005). «Mental wellness of immigrants and refugees». Community Psychological State Journal. 41 (5): 581–597. CiteSeerX 10.1.1.468.6034. doi:10.1007/s10597-005-6363-1. PMID 16142540.
- ^ a b c d National Institute on Alcohol Abuse and Alcoholism. (2005). Module 10F: Immigrants, refugees, and alcohol. In NIAAA: Social work education the prevention and treatment of alcohol usage problems (NIH publication). Washington, D.C.
- ^ Caetano R.; Clark C. L.; Tam T. (1998). «Alcohol usage among racial/ethnic minorities: Theory and research». Journal of Alcohol, Wellness, and Analysis. 22 (4): 233–241.
- ^ UNODC. «Understanding Substance Utilize Among Street Children» (PDF). Retrieved 30 January 2014.
- ^ Cottrell-Boyce, Joe (2010). «THE ROLE OF SOLVENTS IN LIVES OF STREET CHILDREN» (PDF). African Journal of Drug & Alcohol Studies. 9 (2): 93–102. doi:10.4314/ajdas.v9i2.64142. Retrieved 28 January 2014.
- ^ a b c d Breitenfeld D.; Thaller V.; Perić B.; Jagetic N.; Hadžić D.; Breitenfeld T. (2008). «Substance abuse in doing musicians». Alcoholism: Journal on Alcoholism and Relevant Addictions. 44 (1): 37–42.
- ^ Dunne, E. M., Burrell, L. I., Diggins, A. D., Whitehead, N. E., & Latimer, W. W. (2015). «Increased risk for substance use and health‐related problems among homeless veterans». The United States Journal on Addictions. 24 (7): 676–680. doi:10.1111/ajad.12289. PMID 26359444.CS1 maint: Multiple names: writers list (link)
- ^ Zlotnick, C., Tam, T., & Robertson, M. J. (2003). «Disaffiliation, substance use, and leaving homelessness». Substance Use & Misuse. 38 (3–6): 577–599. doi:10.1081/ja-120017386.CS1 maint: numerous names: authors list (website link)
- ^ «Treatment Programs for Substance utilize issues – Mental Health». www.mentalhealth.va.gov. Retrieved 2016-12-17.
- ICD-10: F10.1-F19
- ICD-9-CM: 305
- MeSH: D019966
- DiseasesDB: 3961
- MedlinePlus: 001945
- Substance abuse at Curlie
- Adverse Childhood Experiences: danger Factors for Substance Misuse and psychological state Dr. Robert Anda of U.S. Centers for infection Control describes the relation between youth adversity and soon after ill-health, including drug abuse (video)
- The nationwide Institute on Drug Abuse
- Anti-social behaviour
- Child abuse
- Cruelty to animals
- Domestic abuse
- Elder abuse
- Institutional abuse
- Professional abuse
- Proxy abuse
- Psychological abuse
- Physical abuse
- Religious abuse
- Sexual abuse
- Structural abuse
- Verbal abuse
- Abusive power and control
- Child grooming
- Complex post-traumatic stress disorder
- Just-world hypothesis
- Psychological projection
- Psychological trauma
- Traumatic bonding
- Victim blaming
- Victim playing
- Ethanol (alcohol)
- Alcoholic drinks
- Nitrous oxide
- Hazardous solvents
- contact adhesives
- nail polish remover
- Paint thinner
- Mitragyna speciosa
- Energy drinks
- 2C series
- Psychoactive toads
- Peruvian torch
- San Pedro
- Psilocybin / Psilocin
- Psilocybin mushrooms
- Nitrous oxide
- alkyl nitrites
- amyl nitrite
- Amanita muscaria
- Salvinorin A
- Salvia divinorum
- Atropine and Scopolamine
- Atropa belladonna
- Hyoscyamus niger
- Mandragora officinarum
- Hash oil
- Calea zacatechichi
- Silene capensis
- MDMA (Ecstasy)
- Nitrous oxide
- Cannabis cultivation
- Cannabis smoking
- Head shop
- Legal reputation for cannabis within the United States
- Legality of cannabis
- Marijuana Policy Project
- Medical cannabis
- Cannabis and religion
- Stoner film
- Coffee break
- Latte art
- Tea house
- Beer culture
- Beer festival
- Binge drinking
- Diethyl ether
- Drinking games
- Drinking song
- Happy hour
- Hip flask
- Pub crawl
- Sports bar
- Tailgate party
- Wine bar
- Wine tasting
- Cigarette card
- Fashion cigarettes
- Smoking fetishism
- Tobacco smoking
- Club drug
- Counterculture associated with 1960s
- Dance party
- Drug paraphernalia
- Drug tourism
- Needle sharing
- Party and play
- Poly medication use
- Religion and medications
- Sex and drugs
- Coca production in Colombia
- Drug precursors
- Opium manufacturing in Afghanistan
- Rolling meth lab
- Illegal drug trade
- Darknet market
- Drug distribution
- Beer shop
- Cannabis shop
- Liquor store
- Liquor license
- Date rape drug
- Impaired driving
- Drug harmfulness
- Effects of cannabis
- Opioid replacement therapy
- Responsible use
- Drug-related crime
- Fetal liquor spectrum disorder
- Long-term aftereffects of cannabis
- Passive smoking
- of tobacco or other substances
- 1961 Narcotic Drugs
- 1971 Psychotropic Substances
- 1988 Drug Trafficking
- Council regarding the eu choices on designer drugs
- Drug policy
- Supply reduction
- Policy reform
- Demand reduction
- Drug Policy Alliance
- Harm reduction
- Law Enforcement Action Partnership
- Latin America
- Students for Sensible Drug Policy
- Transform Drug Policy Foundation
- Soviet Union
- United States
- Just Say No
- Office of National Drug Control Policy
- School district drug policies
- Arguments pros and cons medication prohibition
- Capital punishment for drug trafficking
- Cognitive liberty
- Designer drug
- Drug court
- Drug possession
- Drug test
- Politics of medication abuse
- War on Drugs
- Mexican Drug War
- Plan Colombia
- Philippine Drug War
- Zero tolerance
- Alcohol legality
- Alcohol consumption
- Anabolic steroid legality
- Cannabis legality
- Annual use
- Lifetime use
- Cigarette consumption
- Cocaine legality
- Cocaine use
- Methamphetamine legality
- Opiates use
- Psilocybin mushrooms legality
- Salvia legality
- Mild cognitive impairment
- Alzheimer's disease
- Vascular dementia
- Pick's disease
- Creutzfeldt–Jakob condition
- Huntington's disease
- Parkinson's disease
- AIDS dementia complex
- Frontotemporal dementia
- Asperger syndrome
- Savant syndrome
- High-functioning autism
- Post-concussion syndrome
- Organic mind syndrome
- Intoxication/Drug overdose
- Physical dependence
- Substance dependence
- Rebound effect
- Double rebound
- Stimulant psychosis
- Schizoaffective disorder
- Schizophreniform disorder
- Brief reactive psychosis
- Disorganized (hebephrenic) schizophrenia
- Paranoid schizophrenia
- Simple-type schizophrenia
- Childhood schizophrenia
- Pseudoneurotic schizophrenia
- Delusional disorder
- Folie deux
- Bipolar disorder
- Bipolar I
- Bipolar II
- Bipolar NOS
- Major depressive disorder
- Seasonal affective disorder
- Atypical depression
- Melancholic depression
- Social anxiety
- Social phobia
- Specific social phobia
- Specific phobia
- Panic disorder
- Panic attack
- Generalized anxiety disorder
- Acute stress reaction
- Adjustment disorder with depressed mood
- Somatization disorder
- Body dysmorphic disorder
- Da Costa's syndrome
- Conversion disorder
- Ganser syndrome
- Globus pharyngis
- Mass psychogenic illness
- Dissociative identity disorder
- Psychogenic amnesia
- Fugue state
- Depersonalization disorder
- Anorexia nervosa
- Bulimia nervosa
- Rumination syndrome
- REM sleep behavior disorder
- Night terror
- sexual interest
- Hypoactive sexual desire disorder
- sexual arousal
- Female sexual arousal disorder
- Erectile dysfunction
- Delayed ejaculation
- Premature ejaculation
- Sexual anhedonia
- Nonorganic vaginismus
- Nonorganic dyspareunia
- Postpartum depression
- Postpartum psychosis
- Sexual maturation disorder
- Ego-dystonic sexual orientation
- Sexual relationship disorder
- Personality disorder
- Impulse control disorder
- Factitious disorder
- Munchausen syndrome
- X-linked intellectual disability
- Lujan–Fryns syndrome
- Conduct disorder
- Emotional/behavioral disorder
- Separation anxiety disorder
- social functioning
- Selective mutism
- Tic disorder
- Tourette syndrome
- Movement disorders
- False pregnancy
- Intermittent explosive disorder
- Psychomotor agitation
- Psychogenic non-epileptic seizures
- Klüver–Bucy syndrome
- Substance intoxication / Drug overdose
- Substance-induced psychosis
- Substance punishment / Substance use condition / Substance-related disorders
- Physical dependence / emotional dependence / Substance dependence
- Alcoholic hallucinosis
- Alcohol withdrawal
- Fetal alcohol range condition (FASD)
- Fetal alcohol problem (FAS)
- Korsakoff's syndrome
- Korsakoff's psychosis
- Wernicke–Korsakoff syndrome
- Wernicke's encephalopathy
- Alcoholic hepatitis
- Alcoholic liver disease
- Auto-brewery syndrome
- Alcohol-related dementia
- Alcoholic hallucinosis
- Alcoholic cardiomyopathy
- Alcohol flush reaction
- Alcoholism (liquor usage disorder)
- Binge drinking
- Effect of caffeine on memory
- Caffeine-induced rest disorder
- Caffeine dependence
- Effects of cannabis
- Long-term aftereffects of cannabis
- Cannabis dependence
- Cocaine intoxication
- Cocaine dependence
- Acute intoxication from hallucinogens (bad trip)
- Hallucinogen persisting perception disorder
- Opioid overdose
- Opioid use disorder
- benzodiazepine: SID
- Benzodiazepine overdose
- Benzodiazepine withdrawal
- Benzodiazepine usage disorder
- Benzodiazepine dependence
- barbiturate: SID
- Barbiturate overdose
- Barbiturate dependence
- Stimulant psychosis
- Amphetamine dependence
- Nicotine poisoning
- Nicotine withdrawal
- Nicotine dependence
- Inhalant punishment: Toluene toxicity
- Combined drug intoxication
- Polysubstance dependence